Buprenorphine is a generic name for a chemical compound and is short for Buprenorphine Hydrochloride and is a semi-synthetic opioid. Suboxone® and Subutex® are brand names of Buprenorphine-based medications. Suboxone contains 4 parts Buprenorphine and 1 part naloxone. Subutex only contains Buprenorphine as an active ingredient. Subutex is used little in the U.S. Some physicians may use it in the very beginning of treatment, or if the patient has a reaction to naloxone. Subutex was used in Europe mostly France for many years. Most physicians prefer Suboxone because it is less abusable due to presence of the naloxone. Suboxone was invented for the U.S. market.